Journal ID : CJOHNS-21-04-2024-11438
[This article belongs to Volume - 55, Issue - 04]

Title : BLOODSTREAM INFECTIONS AND TRENDS OF ANTIMICROBIAL SENSITIVITY PATTERN: A LABORATORY BASED STUDY

Abstract :

This study aimed to identify the bloodstream infections and trends of antimicrobial sensitivity patterns. From July 2023 to December 2023, a 6-month cross-sectional study was conducted to monitor the sensitivity patterns of bacterial isolates. We obtained all accessible culture assays of blood and wound isolates from the Pathology Laboratory in Abbottabad, Pakistan. The investigation comprised 200 blood cultures to find out the sensitivity patterns. Statistical Package for Social Sciences (SPSS) version 25 was used to examine the study samples. Through cross-tabulation (Pearson's chi-square), descriptive statistics and variations in the frequency pattern across the categorical variables were acquired. Additionally, frequencies and percentages representing various bacteria' general antibiotic sensitivity patterns were provided. According to the findings, out of 200 cultures, 62% of the bacteria were gram-negative, and 38% were gram-positive. Out of the 200 patient reports, 68 (34%) were females, and 132 (66%) of the patients were males. Out of the 200 blood cultures analyzed, 144 (72%) showed positive growth, and 56 (28%) showed negative growth. E.Coli exhibits a 100% sensitivity pattern to several antimicrobial medicines, although Klebsiella also demonstrates sensitivity. Staphylococcus aureus is the most often isolated gram-positive bacteria, followed by S. epidermidis. Antibiotic usage must be prudent in light of the significant increase in antimicrobial drugs. Blood culture and sensitivity are required in all medically suspected blood-stream infections (BSIs) to avert the major issue of increasing treatment resistance.

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