Journal ID : CJOHNS-01-06-2023-11370
[This article belongs to Volume - 58, Issue - 04]

Title : Impact of overweight and obesity on clinical profile of Moroccan patients with an infectious disease

Abstract :

Overweight and obese persons represent a vulnerable population at risk of a multiple infections and various diseases that could potentially to further morbidity and mortality. The objective of the present study is to evaluate the potential role of overweight and obesity on the clinical, Para clinical characteristics and COVID-19 severity in a population of SARS-Cov-2 positive cases. This open longitudinal study concerned 2680 outpatients (overweight/obese versus normal weight) followed in the main private hospital accredited by the ministry of health for COVID 19. Demographic, clinical data, anthropometric measurements and radiological data were recorded. Overall, 1512 cases were overweighed and among them 529 were obese, with median BMI of 26.35 Kg/m2and an average BMI exceeding significantly the threshold for overweight in different age groups (p<0.001). Distribution of patients by comorbidity and BMI revealed that the prevalence of obesity was significantly higher in patients with diabetes (p<0.001), with high blood pressure (p<0.001), or with chronic respiratory disease (p=0.017). Moreover, a significant difference was reported in the CT scan results according to the BMI category of patients. Of particular interest, overweight and obese COVID-19 patients were at higher risk of moderate to severer lung damage (OR =1.72, p-value <0.001). Overweight and obesity are prevalent in Morocco and great attention should be made to this vulnerable population to avoid their contamination with SARS-Cov2 and to start treatment in early stage of the disease to limit the development of the severe form of the COVID-19 disease and outcomes complications.

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