Odontogenic Myxoma of the Right Maxilla and Gingivobuccal sulcus presenting as a Sinonasal mass- A Rare Case Report

Odontogenic myxoma is a rare benign tumor with locally aggressive behavior that typically involves the jaw. Here, we report the case of a 27-year-old woman who presented with a recurrent swelling in the right gingivobuccal region, for which she had undergone surgical excisions in 2017, 2021, and 2024, which was histopathologically identified as Angiomatous infected epulis. She later developed a swelling in her right cheek, nasal block, and a mass in the right gingivobuccal sulcus extending to the right nasal cavity in 2025. A heterogenous enhancing mass lesion in the right maxillary region causing erosion of all walls of maxilla extending into the right nasal cavity confirmed by imaging. A diagnosis of Odontogenic myxoma was confirmed by biopsy of the sinonasal mass. The patient underwent Right Total maxillectomy, and a prosthetic obturator was implanted. For recurrence surveillance, she is presently undergoing organized follow-up. This case emphasizes the necessity of radical excision, comprehensive imaging, and strong clinical suspicion when treating unusual, recurring oral lesions.