Journal ID : CJOHNS-09-09-2023-11388
[This article belongs to Volume - 54, Issue - 07]

Title : Survival of chronic hemodialysis patients following SARS-CoV-2 infection in southern Morocco

Abstract :

In March 2020, the first cases of the disease called COVID-19 due to SARS-CoV-2 infection appeared in Morocco threatening the lives of patients with comorbidities. Chronic hemodialysis patients remain a particularly vulnerable population. Our objective was to describe overall survival and determine factors associated with death in chronic hemodialysis patients infected with SARS-CoV-2. Retrospective multicenter study that included all chronic hemodialysis patients hospitalized for COVID 19 at the regional hospital of Agadir in southern Morocco. The diagnostic criteria of COVID 19 were retained according to the recommendations of the Ministry of Health. The overall survival was estimated by Kaplan Meier method. The threshold of significance was set (p< 0.05). A total of 114 chronic hemodialysis patients were identified. The prevalence of SARS-CoV-2 infection was 9.5%. The average age was 61±11 years with a sex ratio M/F of 1.2. Among our patients, 79 patients (69.3%) had one or more comorbidities; diabetes in 44 patients (38.6%) and hypertension in 67 patients (58.8%). The most common symptoms in our patients were dyspnea in 51.8%, fever in 59.6% and cough in 39.5% of patients. All patients had an elevated CRP value, lymphopenia was found in 71 patients (62,3%), and hyperferritinemia in 43 patients (37,7%). twenty seven patients had severe involvement on chest CT. The mortality rate in our study was 13.2% (15 patients). Survival at 10 day was at 88,6%. In multivariate analysis, the factors associated with the risk of death of the patients were the stay in intensive care unit and the presence of pulmonary embolism. This study confirms that the risk of death after SARS-CoV-2 infection is high in dialysis patients, especially in the intensive care units (ICU). Prevention through vaccination and intensification of barrier measures remain among the solutions to improve the management of these hemodialysis patients.

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